Deadly again for AstraZeneca, the efficient Sputnik V in India

Deadly again for AstraZeneca, the efficient Sputnik V in India


Mr. Horacio Arruda, Public Health Director of Horacio Arruda Province, Quebec (Canada) on April 27, local time, issued a notice recording the first death from a blood clot after the injection of AstraZeneca vaccine to prevent COVID -19.

The death of people with AstraZeneca, Sputnik V understands in An Do
People line up outside an immunization clinic in Edmonton, Canada. Photo: Global Look Press

“We have just had the first patient died from thrombosis, cerebral thrombosis, after vaccination AstraZeneca” – Mr. Arruda said.

Arruda said tests at McMaster University’s lab in Hamilton found that antibodies caused problems with platelets in the 54-year-old woman’s blood, leading to death.

According to him, about 400,000 people have received the AstraZeneca Vaxzevria vaccine in Quebec. Three other cases of coagulation are under investigation, including one recovering and two cases that have not been confirmed to be related to the vaccine. Earlier this month, the first case in Canada of a blood clot in a person receiving Vaxzevria injection was also confirmed in a woman in Quebec.

Speaking about the death, Quebec Premier Francois Legault said he was “saddened to learn that a 54-year-old woman with normal health … died from the COVID-19 vaccine”.

In late March, Canada’s National Immunization Advisory Committee (NACI) suspended the use of injections in people under the age of 55 due to rare reports of serious blood clots in Vaxzevria recipients. but later revised its recommendations to make these people vaccinated.

Several vaccine-related coagulation cases have been reported in EU countries and reviewed by the bloc’s pharmaceutical regulatory agency, the European Medicines Agency (EMA). The EMA’s evaluation showed that abnormal blood clots accompanied by low blood platelets were a “very rare” side effect, estimated to occur in one in 100,000 vaccinated people.

The Sputnik V vaccine can prevent the Indian strain

Mr. Alexander Gintsburg, Director of Gamaleya Center, developer of vaccine Sputnik V said that Sputnik V provides enough antibodies to fight against the SARS-CoV-2 virus strain in India.

The death of people with AstraZeneca, Sputnik V understands in An Do
Russia asserted Sputnik V can resist mutation in India.

“If necessary, we would counteract the strain of the virus in India with the high titer antibodies activated by the Sputnik V vaccine. As a rule, it produces 20, 30 or 80 times more antibodies than the level.” needed to inactivate the largest amount of virus in infected people. Sputnik V will be effective against Indian strains “- he said.

At the end of March, the Indian Ministry of Health reported that a new coronavirus variant with mutations E484Q and L452R in protein S was discovered in the country. These mutations help the virus to spread rapidly.

A study published on April 20 showed that the L452R mutation increases the ability of cells to infect human cells in the laboratory. The California variant, which carries the same mutation, is about 20% more contagious than the previous strain.

Some studies show that two major mutations in variant B.1.617 can “evade” the immune system. Therefore, the Covid-19 vaccine may still be effective against B.1.617, but is slightly less effective.

“It is possible that the vaccine will protect the user from the symptoms of serious illness and death, but not against the risk of infection in people with poorer immune responses” – said Ravi Gupta, professor of Cambridge University. know.

There are also indications that people who already have Covid-19 may be re-infected with this variant, especially when their natural immunity weakens over time. Reinfection may be the cause of the second outbreak of Covid-19 in India.

India is facing a terrible wave of Covid-19. Over the past several weeks, both SARS-CoV-2 virus infections and epidemic deaths have increased rapidly. April 26 is the 5th consecutive day that the 2nd most populous country in the world has recorded the number of Covid-19 cases at more than 300,000 cases / day.

Russia and the US are the two leading countries in providing necessary assistance to India. In particular, Russia has gone before confirming the batch of Sputnik V vaccine will be sent to India on May 1. The US side is still evaluating the effectiveness of the AstraZeneca vaccine and then proceeded to procedures to support India with this vaccine.

Hai Lam

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